Arrhythmia/Electrophysiology European Ancestry as a Risk Factor for Atrial Fibrillation in African Americans
نویسندگان
چکیده
Gregory M. Marcus, MD, MAS; Alvaro Alonso, MD, PhD; Carmen A. Peralta, MD, MAS; Guillaume Lettre, PhD; Eric Vittinghoff, PhD; Steven A. Lubitz, MD; Ervin R. Fox, MD, MPH; Yamini S. Levitzky, MD, MPH; Reena Mehra, MD, MS; Kathleen F. Kerr, PhD; Rajat Deo, MD; Nona Sotoodehnia, MD, MPH; Meggie Akylbekova, MS, MD; Patrick T. Ellinor, MD, PhD; Dina N. Paltoo, MPH, PhD; Elsayed Z. Soliman, MD, MSc, MS; Emelia J. Benjamin, MD, ScM; Susan R. Heckbert, MD, PhD; for the Candidate-Gene Association Resource (CARe) Study
منابع مشابه
European ancestry as a risk factor for atrial fibrillation in African Americans.
BACKGROUND Despite a higher burden of standard atrial fibrillation (AF) risk factors, African Americans have a lower risk of AF than whites. It is unknown whether the higher risk is due to genetic or environmental factors. Because African Americans have varying degrees of European ancestry, we sought to test the hypothesis that European ancestry is an independent risk factor for AF. METHODS A...
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BACKGROUND Atrial fibrillation (AF) is the most common arrhythmia in women and is associated with higher rates of stroke and death. Rates of AF are lower in African American subjects compared with European Americans, suggesting European ancestry could contribute to AF risk. METHODS The Women's Health Initiative (WHI) Observational Study (OS) followed up 93,676 women since the mid 1990s for va...
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BACKGROUND Despite a greater burden of risk factors, atrial fibrillation (AF) is less common among African Americans than European-descent populations. Genome-wide association studies (GWAS) for AF in European-descent populations have identified three predominant genomic regions associated with increased risk (1q21, 4q25, and 16q22). The contribution of these loci to AF risk in African American...
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